Introduction Hypertrophic cardiomyopathy (HCM) is a primary myocardial disease commonly caused by pathogenic genetic variants encoding sarcomere proteins. Mavacamten. a first-in-class allosteric inhibitor of cardiac-specific myosin. has demonstrated efficacy and safety in international clinical trials of patients with symptomatic obstructive HCM (oHCM) but clinical evidence for mavaca... https://powerlands.shop/product-category/optimiser/
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